Everything about Fructose 6-phosphate totally explained
Fructose 6-phosphate (also known as the
Neuberg ester) is
fructose sugar
phosphorylated on carbon 6 (ie. is a
fructosephosphate). The β-
D-form of this compound is very common in
cells. The vast majority of
glucose and fructose entering a cell will become converted to this at some point. The name
Neuberg ester comes from the German biochemist
Carl Neuberg.
History
In 1918,
Carl Neuberg found that the compound (only later identified as fructose 6-phosphate) could be produced by mild acid hydrolysis of "Harden-Young ester" (
fructose 2,6-bisphosphate).
Fructose 6-phosphate in glycolysis
Fructose 6-phosphate lies within the
glycolysis metabolic pathway and is produced by isomerisation of
glucose 6-phosphate. It is in turn further phosphorylated to
fructose-1,6-bisphosphate.
Fructose 6-phosphate isomerism
Fructose 6-phosphate has only one biologically active
isomer, the β-
D-form. There are many other isomers, analogous to those of fructose.
Further Information
Get more info on 'Fructose 6-phosphate'.
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